Single Gene Diss, Chromosome Abnormalities, Multifactorial Diss

deoxyribonucleic acid Ab popularities that Manifest as DissYour name HereSTATEMENT OF THE PROBLEMThe purpose is to end point the fol pitifuling questionsUsing our companionship of the elementtic code , transcription and adaptation develop how a bingle factor dis whitethorn hook from a play . Cite an example of a superstar agent dis , explaining what gene has been transmuteed , how this impresss the product of this gene , and how this may affect the wellness of the individual carrying the mutation . If possible enunciate what the specific mutation isUsing your knowledge of replication , meiosis , and binding , explain how a chromosome abnormality may nobble in the offspring of two well-preserved individuals . Cite an example of a chromosome abnormality , explaining what chromosome or chromosomal segment is missi ng or duplicated , and how this may affect the health of the individual carrying the abnormalityNot all wound argon lightheaded to explain , but some (such as breast cancer colon cancer , type 2 diabetes ) tend to reach more often within acc deprivationited families . Using your knowledge of biotechnology , explain how specific DNA abnormalities can be used to determine a mortal`s chances of development some diseases , and how this knowledge may continue the development of the diseaseANSWERSSingle gene dis may face-lift from a mutationSingle gene dis may arise from mutation . The process of transcription and rendition can be disrupted by these forms of mutations . These mutations include virtuoso base interchange that suppress termination of protein translation , alter patterns of mRNA join during transcription (Garden 2002 . A nonher mutation is bingle base omission that definitely changes the outcome of mRNA transcription or the protein deductive reasoning of trans lation . One example of a single cadre dis ! is the reaping hook cell disease . In people with sickle cell disease at least(prenominal) one of the beta hemoglobin subunits in hemoglobin is replaced with hemoglobin S (Genetic Home eccentric , 2007 . Sickle red ink course cells become distorted forming a cell that looks like a sickle .

This distorted red blood cell is uneffective to ripey transfer oxygen and may sometimes encumber up in the blood vessels . The low oxygen might and short life span of sickled red blood cells names genus Anemia to the person afflicted with these heritable dis . This is a form of single base substitution where a normal a mino acid (valine ) is replaced by another one (glutamineChromosome abnormality may arise in the offspring of two healthy individualsThree mechanisms contribute to genetic variation during meiosis and stuffing . These are independent miscellany of chromosomes , crossing over and random fertilization . Within these triple processes is window for chromosome dis to occur . Meiotic nondisjunction , the bereavement of the chromosomes to disjoin and add to to opposite poles , in either the first of all or second meiotic division is the major cause of chromosomal abnormalities (Tissot Kaufman , 2007 . This includes trisomy , which is the mien of 3 chromosomes instead of 2 . raven syndrome , or trisomy 21 , is the classic example of a homo disease caused by autosomal nondisjunction where some , but not all , touched individuals do survive (Tissot Kaufman , 2007 . Trisomy 21...If you want to get a full essay, order it on our website: OrderCus tomPaper.com

If you want to get a full e! ssay, visit our page: write my paper