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Shaun Zandnia haemophilia a) The main symptom of hemophilia is expel. Mild cases may go unnoticed until later in life, when they occur during surgical process or after trauma. In more severe cases, sobering eject may occur without any cause. Internal bleeding may occur anywhere. Bleeding into joints is common. b) (See table below for chart) haemophilia A (clotting component VIII deficiency) is the close to common engineer of the dis guild, occurring at round 1 in 5,00010,000 male births. hemophilia B (factor IX deficiency) occurs at just about 1 in about 20,00034,000 male births. It is very unlikely for a pistillate to be affected c) Current research beas and intercessions under depth psychology include: Recombinant factor VIII factortically engineered to avoid risks of disease transmitting by infusion and also gene therapy. d) Direct transformation Testing For Hemophilia A and B, it is possible to find for mutations indoors the gene. This approach is called look at DNA interrogatory and is the most accurate method for identifying common carriers. A blood sample from the male family member with hemophilia is analyse first. In about 98% of cases, a mutation send word be identified. Next, a blood sample from the woman desiring carrier exam is obtained, and her DNA is checked for the specific mutation.

Such interrogation is performed at specialized laboratories. Results ar generally available in some(prenominal) weeks.  Linkage (Indirect) Testing In some cases of Hemophilia A and Hemophilia B, a mutation cannot be identified. However, it may be poss ible to use indirect or linkage tests to lo! ok on the gene carrier status of females by trailing the gene in the family. Blood samples are obtained from the male with hemophilia and early(a) family members. Patterns of linked DNA in the person with hemophilia are compared to the DNA in family members to check for the same pattern. Linkage examination is not as accurate as direct interrogation and does not provide information for all families. e) The main discourse for hemophilia is...If you want to get a full essay, enact it on our website: OrderCustomPaper.com

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